Adobe has published compatibility information for its software when using macOS 27 Golden Gate.
Apps compatible with macOS 27 Golden Gate
The following Adobe apps are confirmed to be compatible with macOS 27 Golden Gate. Adobe continues to test its remaining apps, and this table will be updated as testing is completed. Adobe recommends that you check their compatibility page periodically for updates.

According to Adobe, almost all Adobe applications have been confirmed to be compatible with macOS 27 Golden Gate in the following versions, however, with Acrobat DC, a bug has been identified whereby the buttons in the [Check for Updates] dialogue box do not respond to clicks from a mouse or trackpad. If this happens, Adobe advises using the keyboard to navigate the dialogue box: press the Tab key to move between options, and press the [Return] or [Space] key to proceed.

